The R18 runs totally ok on E5 / E10, although ethanol does have a wee bit less caloric value. In your case the difference in octane rating is more significant; 89 is rather lowish. I find mine pulls two up a handful of throttle from low revs up hill better on 98 than on 95.
My riding is mostly in first to fourth through mountainous country. A significant portion is without exagerating better suited for my Vespa Primavera 125! There are day long trips on the R18 that I do not exceed the top speed of said dainty Vespa. Switchbacks shifting down to first, up out and down again, repeat. *
For reference you may want to have a look on Google maps for Árchez, Málaga. In three weeks it hostst a classic vehicle meeting. Look at the possible routes
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Even the highways have 8% inclines so going up at the max legal speed of 120 km/h is nicer in fifth.
Anyway, definitely 98 octane yes, tune up nâh; I like it rough

Ah and I´d more happily fork out 1k for a better suited 5 speed gear box rather than 200 for a tune.
* almost a hour local inland roads distance from here, crossing the Los Alazores pass, is the Puerto del Sol. Going down the M-156 is still too much of a challenge. Heck even going up from Periana is, but thát I will tackle. Take the longer route around past the thermal Baños de Vilo, then úp. Per exception solo, no passenger. A charming but challenging extra on this pass is a herd of sheep with territorial males which you are about 50/50 to encounter.